Progressive proliferative glomerulonephritis in a patient with rheumatoid arthritis treated with D-penicillamine.
نویسندگان
چکیده
A 49 year old man with rheumatoid arthritis developed a proliferative glomerulonephritis with progressive renal impairment during treatment with D-penicillamine. His renal function continued to deteriorate after the drug was stopped but improved after treatment with corticosteroids and azathioprine.
منابع مشابه
Bucillamine-Induced Membranous Nephropathy with Crescent Formation in a Patient with Rheumatoid Arthritis: Case Report and Literature Review
Bucillamine is a disease-modifying antirheumatic drug that is structurally similar to D-penicillamine. The major renal side effect of bucillamine and D-penicillamine is proteinuria caused by membranous nephropathy (MN). In addition to MN, combined crescent formation has been occasionally reported in D-penicillamine-induced MN, while crescent formation has been rarely reported in bucillamine-tre...
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D-penicillamine is an effective disease-modifying drug in rheumatoid arthritis, but adverse effects are common and often lead to the cessation of treatment with this agent [1]. A variety of autoimmune disorders may be induced by the drug, either associated with organspecific autoantibodies (e.g. myasthenia gravis or pemphigus vulgaris) or with non-organ-specific autoantibodies (e.g. systemic lu...
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عنوان ژورنال:
- Annals of the rheumatic diseases
دوره 45 1 شماره
صفحات -
تاریخ انتشار 1986